Plague Inc. is a highly strategic and realistic simulation game that challenges players to infect the world with a deadly plague. Developed by Ndemic Creations, the game offers innovative gameplay and is designed specifically for touchscreen devices. With over four billion games played globally, Plague Inc. has become a top game and has received numerous accolades. It has garnered over half a million -star ratings and has been featured in reputable newspapers such as The Economist and The Guardian. The game's developer was even invited to speak at the Center for Disease Control and Prevention (CDC) in Atlanta about the disease models used in the game. Featuring a highly detailed and hyper-realistic world, Plague Inc. offers advanced AI for outbreak management. The game provides comprehensive in-game help and tutorial systems to assist players. With different disease types, each requiring different strategies, players must evolve their plague to overcome the defenses of humanity. The game allows for full save/load functionality and offers the opportunity to infect over countries, evolve hundreds of traits, and adapt to thousands of world events. Plague Inc. also supports scoreboards and achievements, and expansion updates introduce new challenges such as the mind-controlling Neurax Worm and the zombie-producing Necroa Virus. Plague Inc. has been praised for its ability to engage the public on serious public health topics. The CDC commended the game for creating a compelling world that raises awareness about public health issues. The Coalition for Epidemic Preparedness Innovations highlighted the game's ability to showcase the complexities of a global pandemic response and the importance of international collaboration. Despite the dark subject matter, Plague Inc. has been lauded for its fun and addictive gameplay. It has won awards such as "Overall Game of the Year" from Pocket Gamer and has been described as "killing billions has never been so fun" by IGN. The game is available in multiple languages and continues to receive updates and expansions.